In the herbal product processing industry, controlling environmental conditions, especially during critical production stages, is essential. Building a clean room is crucial to ensure the quality, safety, and durability of herbal products. In this article, we will review the key steps for constructing a clean room specifically for herbal product processing.
In the herbal product processing industry, controlling environmental conditions, especially during critical production stages, is essential. Building a clean room is crucial to ensure the quality, safety, and durability of herbal products. In this article, we will review the key steps for constructing a clean room specifically for herbal product processing.
A clean room is a controlled environment where the concentration of airborne particles (such as dust, microbes, and suspended particles) is strictly regulated. In herbal product processing, including herbal medicines, extracts, and supplements, clean rooms are essential to prevent microbial contamination and to ensure high product quality.
The first step is to identify production requirements:
Type of herbal products
Production capacity
Target standards (such as GMP, HACCP, ISO)
Based on this information, the initial layout of the clean room, including areas like entrance, gowning rooms, production spaces, and quality control zones, should be carefully designed.
The clean room class (ISO 5 to ISO 8) should be selected based on product sensitivity. For most herbal products, ISO 7 or ISO 8 is typically sufficient unless special processes are involved.
Walls, ceilings, and floors must be made from washable and chemical-resistant materials. Sandwich panels with antibacterial coatings are commonly used in clean room construction.
An HVAC system with HEPA filtration must be installed to control temperature, humidity, and airborne particles.
Maintaining positive air pressure inside the clean room is crucial to prevent contamination from external environments.
Herbal processing equipment must comply with GMP standards and be installed in a way that minimizes contamination risks.
After construction, environmental parameters (airborne particles, temperature, humidity, air pressure, and microbial contamination) must be monitored using precise instruments. Finally, the clean room must be validated by authorized bodies to ensure full compliance.
Building a clean room for herbal product processing is a complex and specialized process that requires precise design, use of standard materials, and strict adherence to health and safety protocols. Clean rooms significantly enhance the quality, safety, and shelf-life of herbal products.
